The new plan responds to a shared vision for fishing and aquaculture, aims to deliver impact in five outcome areas, supported through implementation of five cross-cutting enabling strategies. Consultation focused around scenario planning, which can be helpful when planning in an uncertain environment. The plan was informed by a series of reviews, research and extensive consultation. The R&D Plan 2020–25 forms a central part of the strategic planning process that drives organisational focus and impact. On 18 June 2020, the Assistant Minister Jonathon Duniam approved the FRDC’s Research and Development (R&D) Plan 2020–25. The FRDC’s new Research and Development Plan 2020–25 The letter of transmittal (beginning on page v) also forms part of the board’s report of operations and outlines some of the broader issues faced in the operating environment. The following sections summarise the key issues the board addressed during the year. Recreational fishing is seeing a resurgence in participation in areas not COVID-19 locked down. Likewise, there were rays of hope where companies changed direction and showed how perseverance and commitment even in dark times can still lead to good results. However, despite the impacts the crisis brought out the best in many, with people reaching out to provide support and offer a helping hand to those in need. Unlike previous disasters, it was clear that no two people had the same story - even those in the same fishery or business. Over the last six months both directors and staff spoke with people from across fishing and aquaculture to gauge how they were faring, looking for ways to assist. Impacts ranged from direct financial constraints through to personal (physical and mental) and broader community issues. Ocean heat waves, bush fires and the coronavirus pandemic placed huge pressures on both stakeholders and staff. In the second half of the year the story was quite different. Recreational fishing remained a popular pastime, and FRDC’s Indigenous Reference Group was providing excellent input to a wide range of initiatives across Government. In particular, the aquaculture sector continued to see good growth and investment. For the first half of the year, the outlook was positive across all fishing and aquaculture. ( F) Scatter plots comparing histological scores (Ishak lobular inflammation, Ishak portal inflammation, Ishak periportal hepatitis, Ishak fibrosis, and perisinusoidal fibrosis scores) with total, lobular, and portal CD45 + cell density per mm 2 for 28 IA (red diamond) and 6 IT (blue X) subjects, with Spearman’s correlations and P values.The FRDC, like many organisations across Australia, has had a mixed, stressful, but relatively successful year given the events that have developed. A single outlier with portal CD45 + immune cell density at 43,365 was not shown graphically, although it was included in calculating the Spearman’s correlation and P values (shown in red fonts for P < 0.05). ( E) Scatter plots comparing %portal/total area, ALT, HBV DNA, and age relative to total, lobular, and portal CD45 + cell density per mm 2 for 28 IA (red diamond) and 6 IT (blue X) subjects. ( D) Tissue image reproduced with portal and/or lobular location of bile ducts, hepatocytes, and immune cells by applying x/ y spatial coordinates to analyzed IMC data. ( C) Overlay of lobular CD45 –HepPar1 + (green), lobular CD45 +HepPar1 – (purple), and all portal (orange) events show HBsAg expression limited to CD45 –HepPar1 + cells, CK19 expression limited to portal cells, and CD68 expression in both lobular CD45 +HepPar1 – immune cells and portal cells. ( B) Representative contour plot and histogram overlays provide comparisons for portal (red) versus lobular (blue) detection of HepPar1, CD45, and/or CD3 expression, with expected lobular but not portal detection for HepPar1 + hepatocytes and both lobular and portal detection for CD45 + or CD3 + immune cells. Far right contour plot overlay shows that CD68 +CD45 + gate (red) is enriched for concurrent CD16/CD14 expression, compared with CD68 –CD45 + gate (blue). ( A) Acquired IMC images are visualized in representative pseudocolor plots and histogram with overlays to show that HepPar1 + events can be gated separately from CD45 + events, and that CD45 + events are enriched for immune markers (e.g., CD3, CD8, CD68).
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